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After having established a name for itself as one of the outstanding institutes in business studies, took upon itself the challenge of excelling among other colleges in the Science discipline as well. The Pre-Engineering group was introduced in 2003 under the supervision of a very dedicated, experienced and highly motivated science faculty. The Intermediate Pre-Engineering program lays the foundation of the student for professional career in field of Engineering Sciences.

Commecs College one of the best Intermediate colleges in Pakistan, introduced the Pre-Medical group in 2007. The program is at par with the best colleges in Karachi offering Pre-Medical group. The Intermediate Pre-Medical program lays the foundation of students for a professional career in Medicine, Pharmacy, Bio-technology, Food Technology, Bio-chemistry and Microbiology.

Commencing in 1993, the first batch of H.S.C – Commerce passed out in the year 1995, receiving three Merit Positions. Since then the students of Commecs have not looked back. They are set on breaking records. The meritorious achievements of the students of Commecs have placed the college amongst the best commerce colleges in Pakistan.

Intermediate Computer Science program was introduced on the occasion of the 20th anniversary of Commecs College in 2013. The program develops the basic scientific knowledge in the field of Physics, Computer Science and Mathematics through detailed lectures, interactive computer lab sessions and seminars.